Michael Carrick has named Donny van de Beek in his first Manchester United starting XI after making significant changes for tonight’s Champions League showdown with Villarreal.
Summer signing Jadon Sancho also starts with Anthony Martial returning to the starting XI.
Bruno Fernandes, Luke Shaw and Marcus Rashford are among the high profile names on the bench with youngster Amad Diallo also among the subs.
In all, the caretaker boss has made four changes to the side that slumped to a humiliating 4-1 defeat to Watford on Saturday.
Carrick’s line-up would suggest a switch to a 4-3-3 formation.
United are level on points with Villarreal at the top of Group F ahead of kick-off.
A win tonight will guarantee them qualification for the knockout stages of the Champions League.
A draw could prove good enough if Atalanta draw with Young Boys in the group’s other contest.
Man Utd XI: De Gea, Wan-Bissaka, Lindelof, Maguire, Telles, Fred, McTominay, van de Beek, Sancho, Martial, Ronaldo
Subs: Heaton, Henderson, Bailly, Dalot, Fernandes, Lingard, Amad, Matic, Rashford, Mata
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